Characterization of compounds in Cornelian cherry (Cornus mas L.) and its effect on interior milieu in ZDF

Authors

  • Rudolf Dupak Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 949 76 Nitra, Slovak Republic
  • Klaudia Jaszcza Department of Animal Physiology and Endocrinology, University of Agriculture, Al. Mickiewicza 24/28, 30-059 Krakow, Poland
  • Anna Kalafova
  • Monika Schneidgenova Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 949 76 Nitra, Slovak Republic
  • Eva Ivanisova Department of Technology and Quality of Plant Products, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 949 76 Nitra, Slovak Republic
  • Katarina Tokarova Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 949 76 Nitra, Slovak Republic
  • Jan Brindza Department of Genetics and Plant Breeding, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 949 76 Nitra, Slovak Republic
  • Marcela Capcarova Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Trieda Andreja Hlinku 2, 949 76 Nitra, Slovak Republic

DOI:

https://doi.org/10.9755/ejfa.2020.v32.i5.2106

Abstract

The risk of type 2 Diabetes mellitus is constantly increasing and therefore it is necessary to seek effective and new therapies. Cornelian cherry (Cornus mas L.) presents an opportunity in an alternative for treatment of type 2 Diabetes mellitus due its high antioxidant effects. The objective of the study was to assess the effect of Cornelian cherry pulp and stone on ZDF rats, which are suitable biological model for type 2 diabetes. ZDF rats received Cornelian cherry in three doses (1500, 2000 mg kg-1 body weight of the pulp and 250 mg kg-1 body weight of the stone) using the sterile oral rodent gavage for 4 months. Blood glucose, insulin, antioxidant activity and compounds in Cornelian cherry were determined to investigate the effects. Cornelian cherry stone significantly decreased affected blood glucose levels in ZDF rats when compared to the untreated control group. Total polyphenols and phenolic acids had significantly higher values in Cornelian cherry stone against pulp. Also, high concentrations of the anthocyanins were determined in the pulp. The results suggest that Cornelian cherry stone would potentially provide promising source of natural antioxidants and use in the management of Diabetes mellitus.

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Published

2020-05-14

How to Cite

Dupak, R., K. Jaszcza, A. Kalafova, M. Schneidgenova, E. Ivanisova, K. Tokarova, J. Brindza, and M. Capcarova. “Characterization of Compounds in Cornelian Cherry (Cornus Mas L.) and Its Effect on Interior Milieu in ZDF”. Emirates Journal of Food and Agriculture, vol. 32, no. 5, May 2020, pp. 368-75, doi:10.9755/ejfa.2020.v32.i5.2106.

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Section

Research Article