CYTOTOXIC ACTIVITY IN TAGETES LUCIDA CAV. ?

Authors

  • Jorge A. Mejia-Barajas Instituto de Investigaciones Quimico Biologicas, University Michoacana of San Nicolas de Hidalgo, Ed. B-3, Cuidad Universitaria, Francisco J. Mujica, Morelia, Michoacan, C. P. 58060, Mexico
  • Jorge A. Mejia-Barajas Instituto de Investigaciones Quimico Biologicas, University Michoacana of San Nicolas de Hidalgo, Ed. B-3, Cuidad Universitaria, Francisco J. Mujica, Morelia, Michoacan, C. P. 58060, Mexico
  • Rosa E. N. Del Rio Instituto de Investigaciones Quimico Biologicas, University Michoacana of San Nicolas de Hidalgo, Ed. B-3, Cuidad Universitaria, Francisco J. Mujica, Morelia, Michoacan, C. P. 58060, Mexico
  • Rosa E. Martinez-Muñ oz Instituto de Investigaciones Quimico Biologicas, University Michoacana of San Nicolas de Hidalgo, Ed. B-3, Cuidad Universitaria, Francisco J. Mujica, Morelia, Michoacan, C. P. 58060, Mexico
  • Alberto Flores-Garcia and Mauro M. Martinez-Pacheco Instituto de Investigaciones Quimico Biologicas, University Michoacana of San Nicolas de Hidalgo, Ed. B-3, Cuidad Universitaria, Francisco J. Mujica, Morelia, Michoacan, C. P. 58060, Mexico

Keywords:

Citotoxicity, coumarins, T. lucida

Abstract

Tagetes lucida (common name Santamaria) is a native herb widely used in the area with an important economic potential. It has several uses, such as, food, antiseptic, to control diseases infectious and spirituals. The objective of this work was to determine the agent of the cytotoxic activity from T. lucida. 17 straw extracts from different organs of T. lucida were obtained by cold maceration (methanol:chloroform), successive maceration (hexane, dichloromethane and methanol), infusion and extraction Soxhlet (ethyl acetate). The mostly of the plant extract were citotoxic to the crustacean A. salina. Hexanic extracts were notable for their cytotoxic effect. They were purified the 7-methoxycoumarin and 6,7-dimethoxycoumarin from leaf hexanic extract and both compounds caused citotoxicity in A. salina, with LC50 values of 28 and 238 µg/ml, respectively. We find that the cytotoxic effect observed in T. lucida is due to the coumarins.

Downloads

Download data is not yet available.

Published

2017-11-01

How to Cite

Mejia-Barajas, J. A., J. A. Mejia-Barajas, R. E. N. D. Rio, R. E. M.-M. oz, and A. F.-G. and M. M. Martinez-Pacheco. “CYTOTOXIC ACTIVITY IN TAGETES LUCIDA CAV. ?”. Emirates Journal of Food and Agriculture, vol. 24, no. 2, Nov. 2017, pp. 142-7, https://ejfa.me/index.php/journal/article/view/755.

Issue

Vol 24, Issue 2, 2012

Section

Regular Articles

Most read articles by the same author(s)