@article{Habashy_Atta_Ba_Gedara_2021, title={Toxicological Effects of Compounds from the Leaves of Schinus terebinthifolius Against Two Tetranychid Mites (Acari: Tetranychidae)}, volume={33}, url={https://ejfa.me/index.php/journal/article/view/2731}, DOI={10.9755/ejfa.2021.v33.i7.2731}, abstractNote={<p>The use of synthetic acaricides is becoming increasingly hazardous to non-target organisms. Plant-derived natural products are alternative candidates with general low toxicity to human and environment.  Two extracts and nine phenolic compounds (<strong>1</strong>-<strong>9</strong>) from the leaves of the Brazilian pepper tree (<em>Schinus</em> <em>terebinthifolius</em> Raddi) were investigated for their acaricidal effects against two tetranychid mites, <em>Tetranychus</em><em> cinnabarinus </em>(carmine spider mite) and <em>Tetranychus</em><em> urticae</em> (two-spotted spider mite). After 7-days of treatment, the ethyl acetate fraction demonstrated remarkable mortality against <em>T. cinnabarinus </em>(86.67%) while, the <em>n</em>-hexane fraction showed the highest mortality against <em>T. urticae</em> (96.67%) at 200 μg/mL. Among the tested compounds, afzelin (<strong>2</strong>) and protocatechuic acid (<strong>7</strong>) exhibited remarkable activity. Regarding <em>T. cinnabarinus, </em>afzelin showed the highest mortality (86.67%), toxic activity (LC<sub>50</sub> 22.32 μg/mL and toxicity index, Ti 0.972), and the fastest lethality by time<em>.</em> Whereas, protocatechuic acid achieved the highest mortality (96.67%), the lowest LC<sub>50 </sub>(0.232 μg/mL, Ti 73.71), and fastest lethality by time against <em>T. urticae</em>. This study reported a promising <em>in vitro</em> acaricidal activity of the phytoconstituents of the Brazilian pepper tree and suggested its isolated compounds, such as afzelin and chatechuic acid, as alternative leads for the development of echo-friendly acaricides.</p>}, number={7}, journal={Emirates Journal of Food and Agriculture}, author={Habashy, Mariam G. and Atta, Doaa A. Abou El and Ba, Fatma M. Abdel and Gedara, Sahar R.}, year={2021}, month={Aug.}, pages={613–620} }