COMPARISON OF THE ANTIMICROBIAL ACTIVITY OF SEED PROTEIN EXTRACTSFROM SIX MEDICINAL PLANTS AGAINST STAPHYLOCOCCUS AUREUS 6736152

Abstract

A large group of antimicrobial compounds termed as "natural antibiotics" are active against a large spectrum of microorganisms, including bacteria and filamentous fungi in addition to protozoan and metazoan parasites. The present study was conducted to investigate the antimicrobial peptides efficacy from six medicinal plants (Azadirachata indica, Feniculum vulgare, Pegnanum hermala, Ricinus communis, Ocimum basilicum and Cichorium intybus) against Staphylococcus aureus 6736152. The extraction was carried out in Potassium phosphate buffer, Sodium phosphate buffer and Sodium acetate buffer. The antimicrobial activities of these plants were determined by microbiological technique using disc diffusion method against Staphylococcus aureus 6736152. The minimum inhibitory concentrations (MICs) of these plants were also investigated. All the extracts exhibited antibacterial activity against Staphylococcus aureus 6736152 but the stronger antibacterial activity was observed in Peganum hermala extract against Staphylococcus aureus with 40±1.5mm zone of inhibition. Our results showed that the Pegnanum hermala is a rich source for antimicrobial peptides and it may be used for industrial extraction and isolation of antimicrobial compounds which may found place in medicine industry as constituents of antibiotics.